Short bowel syndrome

Use of teduglutide in adults with short bowel syndrome-associated intestinal failure

Nutr Clin Pract .2023 Jun 9. doi: 10.1002/ncp.11015. Online ahead of print. Loris Pironi, Johane P Allard, Francisca Joly, Parnia Geransar, Elisabeth Genestin, Ulrich-Frank PapePMID: 37294295 DOI: 10.1002/ncp.11015 Abstract Short bowel syndrome (SBS) is a rare gastrointestinal disorder associated with intestinal failure (SBS-IF) and poor health-related outcomes. Patients with SBS-IF are unable to absorb sufficient nutrients or fluids to maintain significantly metabolic […]

Use of teduglutide in adults with short bowel syndrome-associated intestinal failure Weiterlesen »

Orally compensated short bowel patients are thin, potentially malnourished but rarely sarcopenic

Clin Nutr. 2023 Aug;42(8):1480-1490. doi: 10.1016/j.clnu.2023.05.018. Epub 2023 May 25. Karen Bannert, Cathleen Karbe, Robert H Förster, Lea F Sautter, Fatuma Meyer, Luzia Valentini, Mats L Wiese, Luise Ehlers, Peggy Berlin, Robert Jaster, Ali A Aghdassi, Markus M Lerch, Georg LamprechtPMID: 37311685 DOI: 10.1016/j.clnu.2023.05.018 Abstract Background & aims:  In short bowel syndrome, insufficient absorptive capacity of the remnant bowel may lead to metabolic and nutritional consequences including electrolyte disturbances, severe

Orally compensated short bowel patients are thin, potentially malnourished but rarely sarcopenic Weiterlesen »

Dapiglutide, a novel dual GLP-1 and GLP-2 receptor agonist, attenuates intestinal insufficiency in a murine model of short bowel

JPEN J Parenter Enteral Nutr. 2022 Jul;46(5):1107-1118. doi: 10.1002/jpen.2286. Epub 2021 Nov 18. Johannes Reiner, Peggy Berlin, Jascha Held, Johanna Thiery, Jolanta Skarbaliene, Jonathan Griffin, Wayne Russell, Per-Olof Eriksson, Mark Berner-Hansen, Luise Ehlers, Brigitte Vollmar, Robert Jaster, Maria Witte, Georg LamprechtPMID: 34705281 DOI: 10.1002/jpen.2286 Abstract Background: Extensive intestinal resection may lead to short bowel (SB) syndrome, resulting in intestinal insufficiency or intestinal failure (IF). Intestinal insufficiency and IF involve deficiency of the

Dapiglutide, a novel dual GLP-1 and GLP-2 receptor agonist, attenuates intestinal insufficiency in a murine model of short bowel Weiterlesen »

Chronic intestinal failure

Chirurg. 2022 Feb;93(2):205-214. doi: 10.1007/s00104-021-01423-8. Epub 2021 Jul 15. Jens G Brockmann, Anna Hüsing-Kabar, Katharina Bohlen, Caro Lin Höckelmann, Andreas PascherPMID: 34264370 DOI: 10.1007/s00104-021-01423-8 Abstract The term intestinal failure (IF) is understood as the transient or irreversible loss of the resorptive capacity of the bowels. This includes a multitude of diseases, some of which have anatomical causes and others functional causes. The

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Teduglutide Promotes Epithelial Tight Junction Pore Function in Murine Short Bowel Syndrome to Alleviate Intestinal Insufficiency

Dig Dis Sci. 2020 Dec;65(12):3521-3537. doi: 10.1007/s10620-020-06140-6. Epub 2020 Feb 19. Johannes Reiner, Peggy Berlin, Jakob Wobar, Holger Schäffler, Karen Bannert, Manuela Bastian, Brigitte Vollmar, Robert Jaster, Georg Lamprecht, Maria WittePMID: 32072437 DOI: 10.1007/s10620-020-06140-6 Abstract Background: In short bowel syndrome, epithelial surface loss results in impaired nutrient absorption and may lead to intestinal insufficiency or intestinal failure. Nucleotide oligomerization domain 2 (Nod2) dysfunction predisposes to the development of

Teduglutide Promotes Epithelial Tight Junction Pore Function in Murine Short Bowel Syndrome to Alleviate Intestinal Insufficiency Weiterlesen »

Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography

Nutrition. 2019 Jul-Aug;63-64:134-140. doi: 10.1016/j.nut.2019.02.001. Epub 2019 Feb 13. Viola Knop, Sophie-Charlott Neuberger, Sabine Marienfeld, Jörg Bojunga, Eva Herrmann, Thierry Poynard, Stefan Zeuzem, Irina Blumenstein, Mireen Friedrich-RustPMID: 30959382 DOI: 10.1016/j.nut.2019.02.001 Abstract Objective: Patients with short bowel syndrome (SBS) receiving long-term parenteral nutrition (PN) are at risk for intestinal failure-associated liver disease (IFALD). The aim of the present study was to evaluate dynamic changes of liver fibrosis and

Intestinal failure-associated liver disease in patients with short bowel syndrome: Evaluation by transient elastography Weiterlesen »

Intestinale Rehabilitation bei Kurzdarmsyndrom und chronischem Darmversagen

Dtsch Med Wochenschr 2019; 144(15): 1061-1066 Ulrich-Frank Pape, Sebastian MaasbergDOI: 10.1055/a-0651-4481 Abstract Patients with severely orally decompensated malsaborption due to surgical rescetion suffer from short bowel syndrome (SBS). The resultant decrease in intestinal surface area after rescetion of parts of the intestines leads to chronic functional intestinal insufficiency or even complete failure (cIF) which requires parenteral

Intestinale Rehabilitation bei Kurzdarmsyndrom und chronischem Darmversagen Weiterlesen »

Starch Tolerance and the Short Bowel

Starch Tolerance and the Short Bowel. J Pediatr Gastroenterol Nutr. 2018 Jun;66 Suppl 3:S68-S71. Jan de Laffolie, Hassan Y Naim, Silvia Rudloff, Klaus-Peter ZimmerPMID: 29762383 DOI: 10.1097/MPG.0000000000001962 Abstract Short bowel syndrome with intestinal failure is a rare disease with a massive impairment in quality of life, requiring a multidisciplinary team approach to medical, surgical, and nutritional therapy. Current pharmacological and

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Five-year survival and causes of death in patients on home parenteral nutrition for severe chronic and benign intestinal failure.

Joly F, Baxter J, Staun M, et al.: Five-year survival and causes of death in patients on home parenteral nutrition for severe chronic and benign intestinal failure. Clin Nutr 2017; 37: 1415–22.PMID: 28701261 DOI: 10.1016/j.clnu.2017.06.016 Abstract Background & aim: Home parenteral nutrition (HPN) is the primary treatment for chronic intestinal failure (IF). Intestinal transplantation (ITx) is indicated when

Five-year survival and causes of death in patients on home parenteral nutrition for severe chronic and benign intestinal failure. Weiterlesen »

Endocytosis in enterocytes

2016 May;166(7-8):205-10. doi: 10.1007/s10354-016-0448-z. Epub 2016 Mar 18.Endocytosis in enterocytes Klaus-Peter Zimmer, Jan de Laffolie, Maria Vittoria Barone, Hassan Y NaimAffiliationsPMID: 26993488 DOI: 10.1007/s10354-016-0448-z Abstract Endocytosis is a fundamental cell biological process, which carries out essential functions in a polarized epithelial cell such as enterocytes provided with a huge surface area of the brush border membrane. Major tasks

Endocytosis in enterocytes Weiterlesen »

The continued rise of paediatric home parenteral nutrition use: Implications for service and the improvement of longitudinal data collection

Clin Nutr. 2015 Dec;34(6):1128-32. doi: 10.1016/j.clnu.2014.11.009. Epub 2014 Nov 20.The continued rise of paediatric home parenteral nutrition use: Implications for service and the improvement of longitudinal data collection Andrew R Barclay, Paul Henderson, Henry Gowen, John Puntis; BIFS collaboratorsPMID: 25476040 DOI: 10.1016/j.clnu.2014.11.009 Abstract Background & aims: Robust data from the United Kingdom (UK) regarding the

The continued rise of paediatric home parenteral nutrition use: Implications for service and the improvement of longitudinal data collection Weiterlesen »

Home Parenteral Nutrition in Adult Patients With Chronic Intestinal Failure: The Evolution Over 4 Decades in a Tertiary Referral Center

JPEN J Parenter Enteral Nutr. 2017 Sep;41(7):1178-1187. doi: 10.1177/0148607116655449. Epub 2016 Jun 20.Home Parenteral Nutrition in Adult Patients With Chronic Intestinal Failure: The Evolution Over 4 Decades in a Tertiary Referral CenterChristopher Filtenborg Brandt, Mark Hvistendahl, Rahim M Naimi, Siri Tribler, Michael Staun, Per Brøbech, Palle Bekker JeppesenPMID: 27323776 DOI: 10.1177/0148607116655449 Abstract Background/aims: In Denmark,

Home Parenteral Nutrition in Adult Patients With Chronic Intestinal Failure: The Evolution Over 4 Decades in a Tertiary Referral Center Weiterlesen »

S3-Guideline of the German Society for Nutritional Medicine (DGEM) in Cooperation with the GESKES, the AKE and the DGVS

Lamprecht G et al. S3-Leitlinie der Deutschen… Aktuel Ernahrungsmed 2014; 39: e57–e71 Andrew R Barclay, Paul Henderson, Henry Gowen, John Puntis; BIFS collaborators G. Lamprecht, U.-F. Pape, M. Witte, A. Pascher, und das DGEM Steering CommitteeISSN: 0341-0501 DOI:10.1055/s-0034-1369922 Abstract Introduction: Enteral and parenteral nutrition are the cornerstone for the therapy of short bowel syndrome and intestinal failure. The underlying anatomic

S3-Guideline of the German Society for Nutritional Medicine (DGEM) in Cooperation with the GESKES, the AKE and the DGVS Weiterlesen »

Das Kurzdarmsyndrom in Deutschland

von Websky MW, Liermann U, Buchholz BM, et al.: Das Kurzdarmsyndrom in Deutschland. Der Chir 2014; 85: 433–9. PMID: 24248157 DOI: 10.1007/s00104-013-2605-x Abstract Objective: As data about prevalence and standard of care in short bowel syndrome (SBS) are not available for Germany, this study estimated the prevalence and assessed the medical infrastructure to potentially improve care of SBS

Das Kurzdarmsyndrom in Deutschland Weiterlesen »

Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates.

Wales PW, de Silva N, Kim J, Lecce L, To T, Moore A: Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates. J Pediatr Surg 2004; 39: 690–5. PMID: 15137001 DOI: 10.1016/j.jpedsurg.2004.01.036 Abstract Background: Congenital or acquired neonatal short bowel syndrome (SBS) carries significant morbidity and mortality rates. No accurate population estimates of incidence and mortality

Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates. Weiterlesen »

Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome.

Messing B, Crenn P, Beau P, Boutron-Ruault MC, Rambaud JC, Matuchansky C: Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome. Gastroenterology 1999; 117: 1043–50. PMID: 10535866 DOI: 10.1016/s0016-5085(99)70388-4 Abstract Background & aims: The short bowel syndrome (SBS) may be associated with either transient or permanent intestinal failure, presently treated by parenteral nutrition

Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome. Weiterlesen »

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