Teduglutide Promotes Epithelial Tight Junction Pore Function in Murine Short Bowel Syndrome to Alleviate Intestinal Insufficiency
Dig Dis Sci. 2020 Dec;65(12):3521-3537. doi: 10.1007/s10620-020-06140-6. Epub 2020 Feb 19. Johannes Reiner, Peggy Berlin, Jakob Wobar, Holger Schäffler, Karen Bannert, Manuela Bastian, Brigitte Vollmar, Robert Jaster, Georg Lamprecht, Maria WittePMID: 32072437 DOI: 10.1007/s10620-020-06140-6 Abstract Background: In short bowel syndrome, epithelial surface loss results in impaired nutrient absorption and may lead to intestinal insufficiency or intestinal failure. Nucleotide oligomerization domain 2 (Nod2) dysfunction predisposes to the development of […]